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  • Cost-utility, cost-effectiveness, and budget impact of Internet-based cognitive behavioral therapy for breast cancer survivors with treatment-induced menopausal symptoms

    Publications26 Aug 2019Panaxea|
    coast effectiveness cancer

    Abstract PurposeInternet-based cognitive behavioral therapy (iCBT), with and without therapist support, is effective in reducing treatment-induced menopausal symptoms and perceived impact of hot flushes and night sweats (HF/NS) in breast cancer survivors. The aim of the current study was to evaluate the cost-utility, cost-effectiveness, and budget impact of both iCBT formats compared to a waiting […]

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  • Integrated specialized atrial fibrillation clinics reduce all-cause mortality: post hoc analysis of a randomized clinical trial

    Publications7 Aug 2019Bert Vrijhoef|
    human heart, artrial fibrillation

    Abstract AimsAn integrated chronic care programme in terms of a specialized outpatient clinic for patients with atrial fibrillation (AF), has demonstrated improved clinical outcomes. The aim of this study is to assess all-cause mortality in patients in whom AF management was delivered through a specialized outpatient clinic offering an integrated chronic care programme. Methods and […]

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  • Call for new policies to ensure added benefit of newly approved drugs

    News22 Jul 2019|
    coast effectiveness cancer

    Janne Mewes, Anne Voermans, Bert Vrijhoef. How many of the newly approved drugs provide a substantial benefit to patients? When asking people from the general public their answer would probably be “all of them” or “the majority”. A recently published analysis conducted by researchers of the German health technology assessment agency IQWiG (Wieseler et al. […]

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  • Implementation fidelity of a strategy to integrate service delivery: learnings from a transitional care program for individuals with complex needs in Singapore

    Publications18 Jul 2019|

    Research article published on BMC Health Serv Res. 2019 Mar 19 AUTHORS: Nurjono M , Shrestha P, Ang IYH, Shiraz F, Toh SESS, Vrijhoef H ABSTRACT BACKGROUND: To cope with rising demand for healthcare services in Singapore, Regional Health Systems (RHS) comprising of health and social care providers across care settings were set up to integrate […]

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  • Retrospective evaluation of healthcare utilisation and mortality of two post-discharge care programmes in Singapore

    Publications22 May 2019Bert Vrijhoef|
    research paper

    Abstract Objective To evaluate the impact on healthcare utilisation frequencies and charges, and mortality of a programme for frequent hospital utilisers and a programme for patients requiring high acuity post-discharge care as part of an integrated healthcare model. Design A retrospective quasi-experimental study without randomisation where patients who received post-discharge care interventions were matched 1:1 with unenrolled […]

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  • Assessment of the scientific rigour of randomized controlled trials on the effectiveness of cognitive behavioural therapy and graded exercise therapy for patients with myalgic encephalomyelitis/chronic fatigue syndrome: A systematic review

    Publications10 May 2019Bert Vrijhoef|Anam Ahmed|

    Abstract Cognitive behavioural therapy and graded exercise therapy have been promoted as effective treatments for patients with myalgic encephalomyelitis/chronic fatigue syndrome. However, criticism on the scientific rigour of these studies has been raised. This review assessed the methodological quality of studies on the effectiveness of cognitive behavioural therapy and graded exercise therapy. The methodological quality […]

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