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  • Validation of a questionnaire measuring patient knowledge of atrial fibrillation in an Asian cohort

    Publications24 Apr 2019Bert Vrijhoef|
    Heart Asia

    Abstract BackgroundPoor patient understanding of atrial fibrillation (AF) may contribute to underuse of anticoagulation. There are no validated instruments to measure patient knowledge in Asian cohorts. This study aims to validate a disease-specific questionnaire measuring the level of understanding of AF and its treatment among patients with AF in Singapore. MethodsA 10-item interviewer-administered questionnaire was […]

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  • The cost impact of PCT-guided antibiotic stewardship versus usual care for hospitalised patients with suspected sepsis or lower respiratory tract infections in the US: A health economic model analysis

    Publications23 Apr 2019Panaxea|
    antibiotics

    Abstract BackgroundProcalcitonin is a biomarker that supports clinical decision-making on when to initiate and discontinue antibiotic therapy. Several cost (-effectiveness) analyses have been conducted on Procalcitonin-guided antibiotic stewardship, but none mainly based on US originated data. ObjectiveTo compare effectiveness and costs of a Procalcitonin-algorithm versus standard care to guide antibiotic prescription for patients hospitalized with […]

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  • Is procalcitonin biomarker-guided antibiotic therapy a cost-effective approach to reduce antibiotic resistant and Clostridium difficile infections in hospitalized patients?

    Publications18 Apr 2019|

    Research article published in Omics: a journal of integrative biology, Vol. 22, No. 9 AUTHORS: Steuten L, Mewes J, Lepage-Nefkens I, Vrijhoef H ABSTRACT Antibiotics (AB) can reduce morbidity and mortality in the treatment of patients with sepsis and chronic obstructive pulmonary disease (COPD) exacerbations. Yet, AB overuse or misuse increases antibiotic resistance (ABR) and […]

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  • Integrated healthcare models for rheumatoid arthritis: A descriptive systematic review

    Publications20 Mar 2019Bert Vrijhoef|
    rheumatoid arthritis in hand

    Abstract IntroductionIntegrated people-centred care is a modern approach for addressing healthcare issues related to demographic changes, increasing prevalence of chronic diseases, and restricted resources. By providing an overview of integrated care models for patients with rheumatoid arthritis, we aimed to offer insight into the strategies and interventions that are being used for designing and implementing […]

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  • Implementation fidelity of a strategy to integrate service delivery: learnings from a transitional care program for individuals with complex needs in Singapore

    Publications19 Mar 2019Bert Vrijhoef|
    Healthcare provider

    Abstract BackgroundTo cope with rising demand for healthcare services in Singapore, Regional Health Systems (RHS) comprising of health and social care providers across care settings were set up to integrate service delivery. Tasked with providing care for the western region, in 2012, the National University Health System (NUHS) – RHS developed a transitional care program […]

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  • Assessing the maturity of the healthcare system for integrated care: testing measurement properties of the SCIROCCO tool

    Publications18 Mar 2019Bert Vrijhoef|
    SCIROCCO tool

    Abstract BackgroundThe Scaling Integrated Care in Context (SCIROCCO) tool has been developed to facilitate knowledge transfer and learning about the implementation and scaling-up of integrated care in European regions. To adequately test the functionality of the tool in assessing the maturity for integrated care within regions, this study evaluated its structural validity, internal consistency and […]

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