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  • Evaluating different adoption scenarios for TIL-therapy and the influence on its (early) cost-effectiveness

    Publications31 Jul 2020Panaxea|
    research paper

    ABSTRACT Background: Treatment with tumor-Infiltrating Lymphocytes (TIL) is an innovative therapy for advanced melanoma with promising clinical phase I/II study results and likely beneficial cost-effectiveness. As a randomized controlled trial on the effectiveness of TIL therapy in advanced melanoma compared to ipilimumab is still ongoing, adoption of TIL therapy by the field is confronted with […]

  • Understanding the Attitudes of Clinicians and Patients Toward a Self-Management eHealth Tool for Atrial Fibrillation: Qualitative Study

    Publications7 Jul 2020Bert Vrijhoef|

    ABSTRACT Background: Atrial fibrillation (AF) is the most common heart rhythm disorder and poses a growing disease burden worldwide because of an aging population. A multidisciplinary approach with an emphasis on patient education and self-management has been demonstrated to improve outcomes for AF through the engagement of patients in their own care. Although electronic tools […]

  • Early Cost-Effectiveness of Tumor Infiltrating Lymphocytes (TIL) for Second Line Treatment in Advanced Melanoma: A Model-Based Economic Evaluation

    Publications18 Jun 2020|

    Research article published on Pubmed. 2018 Seotember 15 AUTHORS: Valesca P Retèl, Lotte M G Steuten, Marnix H Geukes Foppen, Janne C Mewes, Melanie A Lindenberg, John B A G Haanen, Wim H van Harten. ABSTRACT Background: An emerging immunotherapy is infusion of tumor infiltrating Lymphocytes (TIL), with objective response rates of around 50% versus […]

  • Shifting care from hospital to community, a strategy to integrate care in Singapore: process evaluation of implementation fidelity

    Publications17 Jun 2020Bert Vrijhoef|

    ABSTRACT Background Accessibility to efficient and person-centered healthcare delivery drives healthcare transformation in many countries. In Singapore, specialist outpatient clinics (SOCs) are commonly congested due to increasing demands for chronic care. To improve this situation, the National University Health System (NUHS) Regional Health System (RHS) started an integrated care initiative,the Right-Site Care (RSC) program in […]

  • Point-of-care diagnostic test for detecting influenza A/B and respiratory syncytial virus in the ER setting in Norway – A cost analysis

    Publications9 Jun 2020Panaxea|

    Health Technology Assessment published on EUHEA conference. 2020 June 4 AUTHOR: Anne Voermans COAUTHORS: Janne Mewes, Tove Ofstad, Thorbjørn Halvorsen, Katalin Érsek, Lotte Steuten. ABSTRACT Objectives: In Norway an average of 1.7% of the population is being diagnosed with influenza every year. New point-of-care (POC) tests for influenza A/B and RSV are available with excellent […]

  • Serious Gaming During Multidisciplinary Rehabilitation for Patients With Chronic Pain or Fatigue Symptoms: Mixed Methods Design of a Realist Process Evaluation.

    Publications22 Mar 2020Bert Vrijhoef|
    Gamen

      ABSTRACT BACKGROUND:Serious gaming could support patients in learning to cope with chronic pain or functional somatic syndromes and reduce symptom burdens. OBJECTIVE:To realize this potential, insight is needed into how, why, for whom, and when it works in actual treatment circumstances. METHODS:Following a realist approach, process evaluations were performed before, during, and after a […]

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