Meet our team

Panaxea is an independent consultancy company spun-out from the University of Twente, Enschede, the Netherlands. The company is led by a board of directors. Panaxea works with a large international network of professionals to best serve our clients and to achieve the highest level of flexibility.

Hubertus J.M. Vrijhoef, PhD CEO

Hubertus J.M. Vrijhoef, PhD


Dr Bert Vrijhoef is an internationally renowned expert in innovating care for people with chronic diseases and elders. The main themes in his work are: care coordination, eHealth, task shifting and teamwork, self-management support, and the advancement of applied health services and policy research. He leads multiple scientific studies at Tilburg University, Maastricht University Medical Center, Vrije Universiteit Brussel, National University Singapore, and National University Health System in Singapore. He has been/is a partner in various large-scale, international research partnerships, including DISMEVAL (2009-2011), Project INTEGATE (2013-2016), and Scirocco (2016-2019). His scientific work is translated in 200+ publications in (inter)national journals, book chapters and key-note lectures. Multiple individuals have been coached by Bert during their Bachelor, Master and/or PhD training at universities in different countries. Further, he frequently acts as a consultant for stakeholders from different healthcare systems. Bert is the Editor-in-Chief of the International Journal of Care Coordination and member of the editorial board of ICT & Health. He holds a Master’s degree in Health Policy and Management from Erasmus University (1996) and a PhD-Degree in Medical Sociology from Maastricht University (2002). Bert has received various awards for his work, including the Commonwealth Fund’s Harkness Fellowship in Health Care Policy and Practice (2008/09). He shared his opinions via Twitter and LinkedIn.

Isabelle Lepage-Nefkens, PhD, MPH Senior Consultant/Researcher

Isabelle Lepage-Nefkens, PhD, MPH

Senior Consultant/Researcher

Dr Isabelle Lepage-Nefkens (PhD, MSc, MPH) graduated in 1999 from the KULeuven (Belgium) as a bio-engineer in Cell and Gene-technology. Shortly after that, she left abroad for professional development and subsequently has spent more than ten years in different corners of the world including USA, Germany, Hong Kong and Singapore. After finishing her PhD at the Wistar Institute in Philadelphia and Johannes Gutenberg University in Mainz (Germany), Isabelle Lepage-Nefkens has post-doc positions at the Rega Institute in Leuven (Belgium) and Pasteur Institute in Hong Kong, developing a strong research background in molecular biology, infectious diseases, neurobiology and gene technology. Continuing in Singapore, she headed the multicultural and multidisciplinary virology team of a biotech company in pre-clinical drug development for hepatitis C and influenza. She complemented her scientific background with a Master in Public Health with a strong focus on health economy and health policy. Dr Lepage-Nefkens acquired international expertise in Health Services Research for example at KCE (Knowledge centre for healthcare in Belgium). Since 2009 Isabelle Lepage-Nefkens provides consultancy services in the field to governmental organisation, biotech and pharmaceutical firms or other health care organisations, covering aspects such as health services organisations and management, health policy and strategy, health economics, market access, medical science liaison, etc.

Janne Mewes, PhD Senior Consultant/Researcher

Janne Mewes, PhD

Senior Consultant/Researcher

Dr Janne Mewes holds Bachelor’s degree in Health Sciences from the University of Twente in Enschede and a Master’s degree in Health Systems and Public Policy from the University of Edinburgh. After finishing her studies, she interned with the Bertelsmann Foundation in Germany in the Health Policy Monitor and in a project on practice variation. She then returned to the University of Twente, where she started her PhD in 2011. In her thesis, which she defended in 2016, she analysed the cost-effectiveness and budget impact of rehabilitation for cancer survivors. Before joining Panaxea in July 2016, Janne Mewes worked as a post-doc in the Netherlands Cancer Institute, in which she analysed the budget impact of next-generation sequencing for cancer patients.

Anam Ahmed, MSc Junior Consultant/ Researcher

Anam Ahmed, MSc

Junior Consultant/ Researcher

Anam Ahmed, MSc, studied Biomedical Sciences at the VU University in Amsterdam. A strong interest in creating and facilitating bridges between health sciences and the practical field made her obtain her Master’s degree in Science and Business Management at Utrecht University.
During her graduation project, she analysed growth opportunities driven by the strategic objectives of a fast-growing consumer healthcare company. She conducted a feasibility study on the implementation of a new medical device in the Dutch market by performing extensive qualitative and quantitative analyses.
Before joining Panaxea, Anam has worked as a consultant in the field of strategy and analytics. Her passion for health economics made her switch to a career with a stronger focus on life sciences and healthcare innovation.
At Panaxea, Anam uses her scientific background and experience in consultancy to lead innovative projects. She specializes in the health services research field using mixed methods approaches. Since 2019, she is conducting her PhD research at the Radboudumc at the department of primary care and community care. Her PhD focuses on the effectiveness of integrated, person-centred care for vulnerable groups.

Anne Voermans, MSc (ir.) Junior Consultant/Researcher

Anne Voermans, MSc (ir.)

Junior Consultant/Researcher

Anne Voermans, MSc (ir.) graduated as a Medical Engineer from the Eindhoven University of
Technology, which relates to her interest in medical research, especially when innovations are
involved. She worked on (clinical) studies initiated by clinicians throughout different hospitals in the Netherlands before joining Panaxea as a Health Technology Assessment (HTA) consultant in 2018. Anne’s work within Panaxea included the (early) health economic analyses during the CRADL (Continuous Regional Analysis Device for neonate Lung) project under the European Union’s Horizon 2020 research and innovation programme, and the cost-effectiveness analysis of the specific biomarker procalcitonin to guide antibiotic stewardship in sepsis treatment. In 2019, she successfully finished the Health Innovation School. Besides academic skills and practice, Anne has experience working and collaborating with professionals of both different scientific and medical backgrounds.

Josepha Guillaume-Scheffer

Office Manager

Josepha Guillaume-Scheffer has independently managed offices for several organisations including the police and justice department before having been an equestrian entrepreneur and CEO of her own company for 15 years. Having worked throughout Europe and South Africa, setting up a successful international trainer school and having a book published in German and English by Europa’s largest Equestrian publishing house amongst many other things, she has now entrusted her work to the many students she educated while remaining in an advisory capacity. Craving a fresh project at the beginning of 2018, Josepha and Panaxea crossed each other’s path which resulted in her taking on the office manager role at Panaxea as a long-term commitment. For further development, Josepha is pursuing a marketing study.