PANAXEA b.v. is an independent consultancy company spun-out from the University of Twente, Enschede, the Netherlands. The company is led by a board of directors. PANAXEA works with a large international network of professionals to best serve our clients and to achieve the highest level of flexibility.

Isabelle Lepage-Nefkens, PhD, MPH

Chief Executive Officer

Dr. Isabelle Lepage-Nefkens (PH.D., M.Sc., MPH) graduated in 1999 from the KULeuven (Belgium) as a bio-engineer in Cell and Gene-technology. Shortly after that, she left abroad for professional development and subsequently has spent more than 10 years in different corners of the world including USA, Germany, Hong Kong and Singapore. After finishing her Ph.D. at the Wistar Insitute in Philadelphia and the Johannes Gutenberg Universtity in Mainz (Germany), Isabelle Lepage-Nefkens had post-doc positions at the Rega Institute in Leuven (Belgium) and the Pasteur Institute in Hong Kong, developing a strong research background in molecular biology, infectious diseases, neurobiology and gene technology. Continuing in Singapore, she headed the multicultural and multidisciplinary virology team of a biotech company in the pre-clinical drug development for hepatitis C and influenza. She complemented her scientific background with a Master in Public Health with a strong focus on health economy and health policy. Dr. Lepage-Nefkens acquired international expertise in Health Services Research for example at the KCE (Knowledge centre for the health care in Belgium). Since 2009 Isabelle Lepage- Nefkens provides consultancy services in the field to governmental organizations, biotech and pharmaceutical firms or other health care organizations, covering aspects such as health services organization and management, health policy and strategy, health economics, market access, medical science liaison, etc.

Lotte M.G. Steuten, PhD

Chief Scientific Officer

Dr. Lotte Steuten obtained a Master’s Degree in Health Sciences from Maastricht University in 2001 and a PhD (cum laude) in Health Technology Assessment in 2006. Between 2006 and 2008 she was appointed as (senior) research fellow at the Health Economics Research Group / MATCH, Brunel University (UK) and the Department of Health Organization, Policy and Economics at Maastricht University (NL). From 2008 to 2009 she was based in the US and consulted for various large health care organizations in the US (e.g. Kaiser Permanente, Group Health and Fred Hutchinson Cancer Research Center) regarding comparative effectiveness, health technology assessment and health economics.

Hubertus J.M. Vrijhoef, PhD

Chief Innovation Officer

Dr. Hubertus J.M. (Bert) Vrijhoef (Ph.D., M.Sc.) is an international renowned expert in innovating care for people with chronic diseases and elders. Main themes in his work are: care coordination, e-Health, task shifting and teamwork, self-management support, and the advancement of applied health services and policy research. He leads multiple scientific studies at Tilburg University, Maastricht University Medical Center, Vrije Universiteit Brussel, National University Singapore, and National University Health System in Singapore. He has been/is a partner in various large-scaled, international research partnerships, including DISMEVAL (2009-2011), Project INTEGRATE (2013-2016), and Scirocco (2016-2019). His scientific work is translated in 200+ publications in (inter)national journals, book chapters and key-note lectures. Multiple individuals have been coached by Bert during their Bachelor, Master and/or PhD training at universities in different countries. Further, he frequently acts as consultant for stakeholders from different healthcare systems. Bert is the Editor-in-Chief of the International Journal of Care Coordination and member of the editorial board of ICT & Health. He holds a Master-degree in Health Policy and Management from Erasmus University (1996) and a PhD-degree in Medical Sociology from Maastricht University (2002). Bert has received various awards for his work, including the Commonwealth Fund’s Harkness Fellowship in Health Care Policy and Practice (2008/9). He shares his opinions via Twitter and LinkedIn.

Daan Mathijssen, MSc

Junior consultant health economics and outcome research

Daan Mathijssen recently obtained his bachelor and master degree in Health Sciences at Maastricht University. During his bachelor programme from 2011 until 2014 he gained knowledge in the field of human biology, statistics and epidemiology. Afterwards he got interested in health economics and started with the two-year Health Sciences Research Master. During his first year he gained experience in trial-based economic evaluations and cost-effectiveness modelling methods. Furthermore, he followed advance courses in HTA methods, statistics and epidemiology. In the second year he performed his internship at Medtronic and developed an economic evaluation for direct His-bundle pacing. He also went to London to work on a study of informal caregiver’s QoL giving care to patients with Alzheimer disease. In 2016 he graduated from the Health Sciences Research and started working as junior consultant health economics and outcome research at Panaxea.

Anam Ahmed, MSc

Junior consultant health economics and outcome research

Anam Ahmed studied Biomedical Sciences at the Vrije Universiteit in Amsterdam. A strong interest in creating and facilitating bridges between commercial business and the life sciences/ healthcare field, led her to the Master’s program Science and Business Management at the University of Utrecht. During her graduation project she focused on analyzing growth opportunities driven by the strategic objectives of a fast-growing consumer healthcare company. Furthermore, she conducted a feasibility study on the implementation of a medical device in the Dutch market, which included extensive qualitative and quantitative analyses and designing a valuation model. After graduating, she started working as a Consultant focused on strategy, finance and analytics. Her passion for health-economics and market access made her switch to a career with stronger focus on life sciences and healthcare innovation. At Panaxea, Anam uses her scientific background and experience in consultancy to support innovative projects.

Liset Grooten, Msc

Affiliate Junior Reseacher

Liset Grooten holds a Masters degree in Management, Policy Analysis and Entrepreneurship in the Health and Life Sciences from the Vrije Universiteit Amsterdam. She finished her Master thesis in 2014 at the National University of Singapore where she conducted an explorative study on the barriers and facilitators of an integrated care model implemented at a family medicine clinic. Previous to her Master thesis she conducted a research internship at TNO where she performed a literature review on integrated care concepts. Since July 2016 she started her PhD at the Vrije Universiteit Brussel. The research she is conducting for her PhD is part of SCIROCCO, a project co-funded by the European Union. SCIROCCO aims to provide a validated and tested tool that facilitates the successful scaling up and transfer of good practices in integrated care across European regions. The scientific evaluation of SCIROCCO is lead by Panaxea's CIO Dr. Bert Vrijhoef in his capacity of Professor at VUB.

Janne Mewes, PhD

Senior Consultant

Dr. Janne Mewes holds Bachelor´s degree in Health Sciences from the University of Twente in Enschede and a Master´s degree in Health Systems and Public Policy from the University of Edinburgh. After finishing her studies, she interned with the Bertelsmann Foundation in Germany in the Health Policy Monitor and in a project on practice variation. She then returned to the University of Twente, where she started her PhD in 2011. In her thesis, which she defended in 2016, she analysed the cost-effectiveness and budget impact of rehabilitation for cancer survivors. Before joining Panaxea in July 2016, Janne Mewes worked as a post doc in the Netherlands Cancer Institute, in which she analysed the budget impact of next generation sequencing for cancer patients.

Joris van Dijk, MSc

Consultant Benchmarking Hospital Care

Joris van Dijk, MSc obtained a Bachelor Degree in Technical Medicine at the University of Twente (2010). Next, he started his masters in Technical Medine (2010) and Health Sciences (2011). For the latter he received his MSc (Cum Laude) in August 2012. During his master thesis, he performed research on the differences in the estimated outcomes between three methods eligible to quantify patient preferences. In 2012 Joris performed three clinical internships at various departments in several Dutch hospitals (Isala klinieken, Medisch Spectrum Twente, Ziekenhuisgroep Twente). He received his second MSc. Degree (Cum Laude) in July 2014 for his clinical research on the possibilities to introduce and optimize personalized dose in cardiac diagnostics. Currently, Joris combines his work as a PhD candidate in the Isala hospital with his part time function as a healthcare consultant for Panaxea (since March 2013).