News & Cases

November 4, 2021

Panaxea part of joint consortium meeting of the ESCAPE-NET and PARQ projects in Amsterdam

On the 26th and 27th of October, 2021 the joint consortium meeting of the ESCAPE-NET and PARQ projects was held in Amsterdam. ESCAPE-NET is a 5-year project funded by the European Union’s Horizon 2020 program to fund research that improves knowledge, testing, and exploitation platforms that address the future of […]
August 26, 2021

Know your audience: Why report generation is not a one-size-fits-all

Know your audience: Why report generation is not a one-size-fits-all You’ve built a body of evidence to demonstrate your product’s capabilities, value, potential and benefits. But just how technical should your report be? When companies submit reports to payers or regulators, depth and detail matter, but these aren’t the only […]
July 20, 2021

Putting patients at the centre of health care

Article published on International Journal of Care, May 30, 2021 Author: Hubertus JM Vrijhoef On 20 January 2021, when President Joseph Biden was sworn in as the 46th President of the United States of America, the National Patient Advocate Foundation (NPAF) urged him to adopt person-centred health care policies as […]
July 5, 2021

Let the evidence show … Giving the right advice, to the right client, at the right time

Let the evidence show … Giving the right advice, to the right client, at the right time Evidence gathering and knowledge about a product, and its likely success, adapt and change over the life cycle. Early on the focus is on safety, then later on efficacy, effectiveness and ultimately cost-effectiveness; […]
June 24, 2021

Painting the big picture for better healthcare launches

Painting the big picture for better healthcare launches Tunnel vision is a frequent problem with many health and life sciences innovators. They become immersed in a solution or design and forget about the bigger picture – what is the broader problem that the innovation seeks to solve, who will benefit […]
December 8, 2020

PhD defence Melanie Lindenberg

Panaxea’s team member Melanie Lindenberg will defend her thesis this coming Friday. The PhD research has been done at Antoni van Leeuwenhoek, the Netherlands Cancer Institute, under guidance of  prof. dr. W.H. van Harten and dr. V.P. Retèl. The defence can be followed via livestream (in Dutch) starting at 10.45 […]
November 12, 2020

Compilation of publication by Panaxea Researchers from 2012 to 2017

To complete our library of publications from Panaxea’s researchers we’d like to offer you a compilation of all the publications between 2012 and 2017. Please use the search button in the top right corner on this website if you are looking for specific publications or send us an email if […]
November 5, 2020

Care coordination during and beyond the coronavirus: Learning together and faster to strengthen health systems

Care coordination during and beyond the coronavirus: Learning together and faster to strengthen health systems Internationally sharing experiences and lessons in the strengthening of health systems and the rapid reorganising of service delivery into new health ecosystems to respond to COVID19 may also accelerate the coordination of service delivery for […]
November 3, 2020

Panaxea: Adding Evidence to Health Care Innovation

Panaxea: Adding Evidence to Health Care Innovation Improving health care and with that, the lives and health of millions of people, has always been our first and foremost priority. Currently, health care innovation has become even more of a top priority, worldwide. Therefore, we would like to inform you about […]
October 19, 2020

New book published with chapter of Bert Vrijhoef and Valentina Vodopivec

New book published with chapter of Bert Vrijhoef and Valentina Vodopivec The book, titled ‘Integrating the Organization of Health Services, Worker Wellbeing and Quality of Care’ introduces the concept of ‘healthy healthcare’ and posits that this new concept is necessary in light of a shortage of healthcare staff in the […]
October 13, 2020

Panaxea to investigate cost-effectiveness of innovative stem cell treatment for osteoarthritis

Panaxea to investigate cost-effectiveness of innovative stem cell treatment for osteoarthritis As part of the international consortium of the AutoCRAT (Automated Cellular Robot-Assisted Technologies, grant no. 874671) project, Panaxea is evaluating the cost-effectiveness of an innovative robot-assisted platform to manufacture stem cells that can be used to treat osteoarthritis (OA) […]
January 28, 2020

Fourth annual consortium meeting of the ESCAPE-NET project

Fourth annual consortium meeting of the ESCAPE-NET project On the 21st and 22nd of January, 2020 the fourth annual consortium meeting of the ESCAPE-NET project was held in Amsterdam. ESCAPE-NET is a 5-year project funded by the European Union’s Horizon 2020 program to fund research that improves knowledge, testing, and […]
January 13, 2020


Het volgende artikel werd gepubliceerd in, 9 december 2019 GEÏNTEGREERDE ZORG SUCCESVOL IMPLEMENTEREN IS MOEILIJKER DAN EEN LANDING OP DE MAAN TEKST: JENS DE WULF Op maandag 28 oktober was professor Bert Vrijhoef te gast bij Zorgnet-Icuro. Hij voerde er een vurig pleidooi voor geïntegreerde zorg. Vrijhoef, CEO bij […]
November 5, 2019

Veelbelovend onderzoekparadigma voor complexe zorginnovaties

Het volgende artikel werd gepubliceerd in 5 maart 2018 Veelbelovend onderzoekparadigma voor complexe zorginnovaties Door: Bert Vrijhoef, Anam Ahmed, Janne Mewes ‘Realist evaluation’ biedt uitkomst bij het in kaart brengen van de impact van complexe zorginnovaties De gezondheidszorg is op vele fronten tegelijk in beweging. Bij innovatieve interventies willen we […]
October 7, 2019

Gamen leert mensen omgaan met chronische pijn

Het volgende artikel werd gepubliceerd in ICT & Health magazine op pagina 30 en 31  in nummer 4/2019. Gamen leert mensen omgaan met chronische pijn DOOR MIEL VUGTS, MARGOT JOOSEN, AGLAIA ZEDLITZ, INGE BONGERS, BERT VRIJHOEF Meer mensen bereiken met kosteneffectieve interventies is wenselijk, zodat ze leren omgaan met chronische […]
July 22, 2019

Call for new policies to ensure added benefit of newly approved drugs

Janne Mewes, Anne Voermans, Bert Vrijhoef. Call for new policies to ensure added benefit of newly approved drugs How many of the newly approved drugs provide a substantial benefit to patients? When asking people from the general public their answer would probably be “all of them” or “the majority”. A […]
August 29, 2018

‘Future of care – care of the future’ by Bert Vrijhoef

Thinking about care of the future, self-care is increasingly becoming important. At the Self-Care Summit in Copenhagen from 11-12 April 2018, I provided three reasons for thinking so. Firstly, self-care is everywhere. At the level of the individual, everyone practices self-care by making daily choices and lifestyle decisions. Minor ailments, long-term conditions or in-hospital […]
July 27, 2018

What have we been up to at Panaxea?

Looking back at the first half year of 2018… Almost 7  months have already flown by of the new year and Panaxea has not been idle. Read more about the interesting events of the company. Person-centered care in (primary) care practice What is needed for the effective application of person-centered […]
February 14, 2018
Healthcare Netherlands

The challenge of joint decision making with vulnerable people

On January 26th, the congress ‘Joint decision-making with vulnerable people: a challenge’ was held in Utrecht. During this congress, the central question was: ‘What is needed to take decisions about complex issues together with vulnerable people?’ When talking about vulnerable people, we can think of all sorts of people: the […]
February 13, 2018

Persoonsgerichte zorg in de (eerstelijns) zorgpraktijk

Wat is er nodig voor het effectief toepassen van persoonsgerichte zorg in de (eerstelijns) zorgpraktijk? En hoe doen we dat waarbij bijzondere interesse uitgaat naar de invloed van diversiteit op het verlenen van persoonsgerichte zorg? Deze vragen staan centraal in een door het Zorginstituut Nederland geïnitieerd onderzoek dat wordt uitgevoerd […]
November 24, 2017
Digital Healthcare Innovations

Building digital healthcare together

During the 20th edition of the Electronic Commerce Platform (ECP) Annual Congress on November 16th, the building blocks of the digital society were discussed.
July 18, 2017
Health Technology Assessment

Presentation of the Joint European Horizon Scanning System on HTAi conference

During the latest HTAi conference in Rome, themed “Towards an HTA Ecosystem: From Local Needs to Global Opportunities”, CEO Isabelle Lepage-Nefkens presented the proposal for a joint European horizon scanning system (HSS). The joint European HSS proposal was commissioned by the BeNeLuxA collaboration on ministerial level, but several other countries […]
July 11, 2017

Dure geneesmiddelen: een probleem voor de volksgezondheid in Nederland?

Door een toename van diagnose en behandelmogelijkheden neemt de incidentie en prevalentie van zeldzame aandoeningen snel toe. Onder andere als gevolg hiervan groeit ook het aantal geregistreerde weesgeneesmiddelen. Ter vergelijking: in de jaren 2006-2010 werden en 686 registratie-aanvragen ingediend voor weesgeneesmiddelen bij de European Medicine Agency (EMA); tussen 2011-2015 waren […]
June 20, 2017

Big Data in healthcare: more clear, less fear?

On May 18th 2017 the Dutch Ministry of Health, Welfare and Sports in cooperation with the Academic Medical Centre Amsterdam organized a meet-up event called “Big Data in Healthcare: a combination of an un-conference and a hackathon”. Approximately 50 participating experience experts were asked: “What should policy regarding big data […]
May 23, 2017

The scaling up of integrated care: the importance of context

During the 17th International Conference on Integrated Care (ICIC), held in Dublin last week, people from different countries presented strategies on the development, evaluation and/or implementation of integrated care. Although many strategies showed overlap in approaches and face the same challenges, other strategies revealed significant differences between countries. For example, […]
April 7, 2017
medical technology innovations

Panaxea hosts MedtechMeeting in Amsterdam

On 23rd of march 2017 Panaxea hosted the MedtechMeeting at the ‘Silicon Valley’ of Amsterdam: Science Park. This event was organized by MedtechPartners which serve as the accelerator of the development of medical technology innovations in the process to get from idea to a marketable product. The goal of the […]
February 22, 2017

Panaxea’s Janne Mewes about the importance of aftercare in cancer patients for employers

As the incidence of cancer is rising and more patients survive their disease, the number of people within the population who have a history of cancer is rising. Unfortunately, most cancer survivors experience bothersome late and long-term symptoms, such as fatigue, low physical functioning, low quality of life, depression, anxiety, […]
February 22, 2017

The economics of bringing precision medicine to the clinic

Precision Medicine’s value is undeniable. But what about its financial impact? And how should we assess its value? Read the views of Panaxea co-founder dr. Lotte Steuten, as presented at the 2017 Precision Medicine World Conference in Silicon Valley. This presentation will cover the unsustainable economics at play, reimbursement challenges […]
February 6, 2017

Digital health innovations: assessment of their impact on health and economic outcomes

With the ageing population in Europe, an increase in the number of people with chronic diseases, limited health care budgets and the means to treat patients at low cost is becoming more and more of an issue. Recently, a European blueprint was established with the objective of optimizing health care […]
February 1, 2017
Health Economic Modeling

Thermo Fisher Scientific: safely reduce antibiotic exposure

Antibiotics are a limited resource. At the current pace of injudicious use, all antibiotics will soon become ineffective. Panaxea together with Thermo Fisher developed a health-economic model for the use of Procalcitonin (PCT) to determine whether PCT can cost-effectively reduce the use of antibiotics for sepsis. This brochure displays among other […]
October 4, 2016

Integrated care: unlocking the mysteries

Mystery is not a word that we often connect with health and care as these are worlds in which we like to deal with the practical and the real. However it often seems that working out how best to successfully co-ordinate the contribution of different professionals, services and agencies is […]
August 25, 2016
Health Economic Modeling

The broader view of health economics

Thermo Fisher is a long time client of Panaxea. This resulted among others in a tailor made health economic model for the Procalcitonin (PCT) test manufactured by Thermo Fisher. Results of this model were published in the Journal of Medical Economics. Recently, a new study was published by De Jong […]
August 23, 2016

The challenges and opportunities of articulating the value of your diagnostics

We added a new white paper about the challenges and opportunities of articulating the value of your diagnostics! Please click here to download this white paper.
August 17, 2016
Health Care Innovations

Panaxea joins Flanders Innovation & Entrepreneurship

We’re proud to announce that Panaxea is now a certified service provider for the Flemish government under the SME grants from the Flanders Innovation & Enterpreneurship agency ( Flanders Innovation & Entrepreneurship (in Dutch: Agentschap Innoveren & Ondernemen) is a government agency, charged with implementing the economic, innovation and enterprise policy in […]
June 20, 2016

MAFEIP follow up: Panaxea joins European Innovation Partnership on Active and Healthy Ageing Action Groups

Following an earlier involvement with the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA), Panaxea is now a partner for the 2016-2018 period. EIP on AHA EIP on AHA is a policy initiative that aims to share and scale up innovative solutions to improve active and healthy ageing […]
June 20, 2016

Further research for predictive biomarkers

Lotte Steuten worked along with Anna Miquel-Cases, Valesca Retèl, and Wim van Harten on a paper on decision about design and priority of studies of emerging predictive biomarkers of high-dose alkylating chemotherapy (HDAC) in triple-negative breast cancer (TNBC). The paper was published in Value in Health. The information was gathered by a value-of-information […]
June 13, 2016

New VOKA white paper: Value based care innovation and logistics

Panaxea contributed to the new Voka white paper: Value based care innovation and logistics. This white paper shares the vision of a diverse group of stakeholders on the future of value based decisions in health care. The full white paper can be found here (Dutch only). Voka Health Community brings entrepreneurs, health […]
June 6, 2016
Healthcare innovations

From re-search to pro-search: P-value

Innovations in healthcare transform the way healthcare gets delivered and the lives of people. Healthcare is getting person-centred and people are getting proactive. Do you recognize a pattern here? I’m talking about P-value: person-centered and proactive. But how does this translate into the evaluation of healthcare innovations and the assessment […]
June 1, 2016

Organizational innovations to accelerate technology transfer and translational research — Do they work?

Recently, a paper by Lotte Steuten was published in ‘OMICS: A Journal of Integrative Biology’. This paper is a result of a Panaxea project, to promote the need for institutional innovation to cultivate translational research. According to Dr Steuten: Lessons learned from this study may inform future innovation impact assessments […]
May 30, 2016

Senior Consultant Vacancy

Panaxea is seeking to find an experienced and passionate senior consultant with an interest in business development to expand our team. The generation of new clients, the ongoing relationship management with existing clients and the successful management of projects are essential to the growth, security and prosperity of our company. […]
May 26, 2016
Our Future Health

Bert Vrijhoef at Our Future Health

Our Future Health started today with presentations from the Dutch Minister of Health, Welfare and Sport Edith Schippers, and Ex-European Commissioner Neelie Kroes. Tomorrow (27th of May) is the day that Bert will pitch his ideas! He will use this opportunity to pitch his ideas on the innovation of research […]
April 12, 2016

Bert Vrijhoef introduced as speaker at Our Future Health

Our Chief Innovation Officer Bert Vrijhoef is introduced today as a speaker at Our Future Health 2016. The event will find place at Nijmegen on the 26th of May. Other eye-catching speakers are the Dutch Minister of Health, Welfare and Sport Edith Schippers and Ex-European Commissioner Neelie Kroes. More Our […]
April 11, 2016

Results from our Customer Satisfaction Survey

As we understand the critical importance of value-assessments to our customers’ innovations, we regularly ask our customers how they value us! The most recent survey on our customers’ experiences showed that they particularly value the high (scientific) quality of the project deliverables, and the flexible, sharp and pro-active attitude of […]
March 31, 2016
assessment of health

Gimon de Graaf and Lotte Steuten co-authors on web-based tool paper

Gimon De Graaf and Lotte Steuten are co-authors on paper about the development of a web-based tool for the assessment of health and economic outcomes of the European Innovation Partnership on Active and Healthy Aging (EIP on AHA). The aim of the paper was to describe the approach for developing […]
March 16, 2016
ICT in health care

Interview in ICT & Health with Bert Vrijhoef

Bert Vrijhoef shares his views on the implementation of ICT in healthcare at an individual, local and global level. The interview was published in the first volume of ICT & Health in 2016. Because the article is Dutch, some interesting statements of the interview are shared in English: Working in […]
March 7, 2016
Health Care Innovations

Introducing Bert Vrijhoef as our new CIO!

As of March 2015, we are delighted to welcome Prof. dr. Bert Vrijhoef as the Chief Innovation Officer (CIO) of Panaxea. Dr. Vrijhoef is a renowned international expert in the field of health care innovation and its scientific evaluation. Dr. Vrijhoef: “In my work I continuously strive to detect the […]
February 17, 2016

Three take home messages from the Economic Evaluation presentation

The new Dutch economic evaluation guideline was presented yesterday. Panaxea attended this meeting to be aware of this new guideline, and get familiair with the differences between this guideline and the previous edition. The guideline differs in many aspects from the 2006 version. We compiled a list of three changes […]
February 10, 2016
Health Technology Assessment

The new Dutch economic evaluation guideline

All parties in health care, from governments to hospitals, are bound to budgets. The use of economic evaluations helps these parties by determining how their budgets can be spend in the most optimal way. However, it is hard for some of these parties to make economic evaluations themselves or to […]
February 2, 2016

Panaxea takes place in CRADL consortium

Panaxea is proud to announce that it takes place in this consortium with 11 other parties, like the Middlesex University and Amsterdam’s Emma Children’s Hospital. CRADL (which stands for Continuous Regional Analysis Device for neonate Lung) will show how EID can provide new cost effective, easy to use, respiratory management […]
November 9, 2015

Panaxea posters, presentations and workshops @ISPOR Milan 9-11 November 2015

Dear ISPORIAN, Panaxea ( provides customized, high-quality analyses about the added value of products and interventions in the care pathway. We specialize in health economic modeling for diagnostica and medical devices to facilitate market access in Europe. Curious to see how tools developed by Panaxea can be used for the […]
June 3, 2015
Time-and-motion study

Articulating the value of diagnostics

Diagnostics face difficulties in current market conditions to obtain reimbursement and to enter the market efficiently. This white paper highlights the challenges, but more importantly also highlights the opportunities in articulating the value of diagnostics. It is explained why tailored health economic evidence is paramount to show the value of […]
May 19, 2015

Health economic evaluation of a strict glucose control guideline implemented using point-of-care testing in three Intensive Care Units in the Netherlands

Health economic evaluation of a strict glucose control guideline implemented using point-of-care testing in three Intensive Care Units in the Netherlands van Hooijdonk RT1, Steuten LM, Kip MM, Monteban H, Mulder MR, van Braam Houckgeest F, van der Sluijs JP, Abu-Hanna A, Spronk PE, Schultz MJ.
May 19, 2015
Cost effective health model

Generic decision model for diagnostic tests

To give (potential) clients a preliminary insight in the cost-effectiveness of their diagnostic test, we developed an online generic decision model. This model allows users to compare the cost and effects of a diagnostic test versus not testing by using data they collected themselves, for example data they collected during […]
May 19, 2015

Marloes van der Maas joined board “Jong NVTAG”

Jong NVTAG is a Dutch organization that aims to address the need of young professionals in the field of health economics to meet each other, exchange experiences and learn more about the field. Jong NVTAG does this by organizing multiple events per year, each event centered on one theme that […]
April 20, 2015

Long-term cost–effectiveness of Oncotype DX® versus current clinical practice from a Dutch cost perspective

Michelle Kip, Helma Monteban & Lotte Steuten, Long-term cost–effectiveness of Oncotype DX® versus current clinical practice from a Dutch cost perspective, Journal of Comparative Effectiveness Research. Link to publication
March 31, 2015
Panaxea Courses


Building upon our expertise and experience, Panaxea can organize or contribute to courses, seminars and workshops on a wide range of topics in the field of health technology assessment. For this, we can build on years of experience in teaching to students of the University of Twente. In particular, Panaxea […]
March 31, 2015

Introduction course to early Health Technology Assessment by Panaxea

Panaxea has cooperated with the University of Twente department Health Technology and Services Research in developing a one-day introductory course to early health technology assessment.
March 5, 2015

Maarten IJzerman nominated President-elect ISPOR

The International Society for Pharmacoeconomics and Outcomes Research (ISPOR) is a member-driven organization led by a diverse Board of Directors and professional staff who work collaboratively to ensure the organization is strategically positioned and effectively serving its membership. The election for the 2015-2016 ISPOR Board of Directors and President-elect is […]
February 25, 2015

Systematic literature review

For a medical device company developing blood glucose meters, we performed a systematic literature review on self-monitoring of blood glucose levels among patients with type 2 diabetes. The report covered an analysis of the burden of the disease and the cost-effectiveness of blood glucose self-monitoring. Cost tables, specifying the cost […]
February 25, 2015
Cost effective health model

Market access and reimbursement report

A medical device company has developed a new technology that could improve the visualization and treatment of the affected heart tissue during catheter ablations of the left atrium of the heart. They were interested in getting an overview of the market access and reimbursement regulations in the Netherlands and Belgium […]
February 25, 2015
Health Technology Assessment

Cost-effectiveness and budget impact model for a diagnostic test

Allergic Rhinitis (AR) is a condition where an inflammatory reaction of the immune system is caused by specific allergens. Respiratory AR affects around 15% of the people in the Netherlands. Mostly, AR is treated with symptomatic treatment, but immunotherapy potentially offers a curative treatment by minimizing sensitivity to the allergen. […]
September 7, 2014

Panaxea at ISPOR Amsterdam, 10-13 November 2014

Panaxea will be one of the exhibiting organizations at the 17th Annual ISPOR European Congress in Amsterdam (RAI). Visit our booth #913  
September 2, 2014

New office

Our office has been relocated to a new address! Hengelosestraat 221 7521 AC Enschede The Netherlands  [su_gmap address=”Hengelosestraat 221″]
January 22, 2014
Health Economic Modeling

Health Economic Modeling

For a global health company we evaluated the expected incremental cost-effectiveness of one of their products. The cost-effectiveness outcome was needed to support adjuvant therapy decision making versus current clinical practice in the Netherlands. We… developed a Markov model to project distant recurrences survival, quality-adjusted life expectancy and direct medical […]
January 22, 2014
Time-and-motion study

Time-and-motion study

For a large pharmaceutical company, Panaxea was asked to perform a time-and-motion study to compare two administration methods of medicine.
January 22, 2014

Impact-analysis public-private partnership (PPP)

In this project we performed an impact-analysis on scientific, translational/clinical and socio-economic aspects of a public-private partnership (PPP)
January 22, 2014

Health economic analysis of a POCT assay

Point of Care Testing (POCT) is generally perceived to be more expensive on a unit-cost base than testing performed in a centralized laboratory. Consequently, introducing a new treatment protocol in the hospital setting, involving an increase in the number of POCT analyses performed, requires a thorough analysis of accompanying costs […]
January 22, 2014
Decision analytic support model

Decision analytic support model to guide implementation of laboratory assay

Decision analytic support model could be populated with hospital-specific data, and could thereby guide implementation decisions at local and hospital level
January 22, 2014
health economic model

Value dossier and health economic model for a provider of haemodialysis

A large provider of haemodialysis services wanted to increase the market share of one of their products. They requested Panaxea 1) to develop a health economic value story to secure global reimbursement for this technology; 2) and to develop a model incorporating both a cost-effectiveness and budget impact analysis to […]